Hamilton's early film credits included the 1959 opposite and in 1960.
Hamilton in her later years divided her time between the East and West coasts, living at her home in and at her other residence in her hometown of Los Angeles.
She then dated -born actor for more than two decades before they married in 1997.
Tom landed a lead role in the film in 1993, which led to roles in other films such as and.
From there on, she voiced in and had minor roles on , , and before landing her regular roles on , where she voiced Minh and Connie Souphanousinphone and later , where she voices and Inez Wong.
Other animated movies Tom has voiced include , , , , , and the four Futurama movies: , , , and.
Hamilton was also an artist, director, and writer.
Hamilton's honor was part of series of Columbia University's Big Read program, focusing on To Kill a Mockingbird through guest lectures, productions, and panel discussions.